Our Latest Publications

  1. Liu Xue*, Kimmey, J.M. *, Matarazzo, L. *, de Bakker, V., Van Maele, L., Sirard, J.-C., Nizet, V., and Veening, J.-W. (2021). Exploration of Bacterial Bottlenecks and Streptococcus pneumoniae Pathogenesis by CRISPRi-Seq. Cell Host & Microbe 29, 107-120.e6. 10.1016/j.chom.2020.10.001. (Co-first author, IF=17.766)
  3. Liu Xue, Gallay, C., Kjos, M., Domenech, A., Slager, J., van Kessel, S.P., Knoops, K., Sorg, R.A., Zhang, J.R., and Veening, J.W. (2017). High-throughput CRISPRi Phenotyping Identifies New Essential Genes in Streptococcus pneumoniae. Molecular systems biology 13, 931. (Cover paper, IF=9.954)
  1. Liu Xue, Li, J.W., Feng, Z., Luo, Y., Veening, J.W., and Zhang, J.R. (2017). Transcriptional Repressor PtvR Regulates Phenotypic Tolerance to Vancomycin in Streptococcus pneumoniae. Journal of bacteriology 199. (IF=3.252)
  1. Zhang, B. *, Liu Xue *, Lambert, E. *, Mas, G., Hiller, S., Veening, J.-W., and Perez, C. (2020). Structure of a proton-dependent lipid transporter involved in lipoteichoic acids biosynthesis. Nat Struct Mol Biol 27, 561–569. (Co-first author, IF=12.263)
  1. de Bakker, V.*, Liu, Xue*, Bravo, A.M., and Veening, J.-W. (2022). CRISPRi-seq for genome-wide fitness quantification in bacteria. Nat Protoc 17, 252–281. 10.1038/s41596-021-00639- 6. (Co-first author, IF=17.766)
  3. Dewachter, L., Dénéréaz, J., Liu, Xue, de Bakker, V., Costa, C., Baldry, M., Sirard, J.-C., and Veening, J.-W. (2022). Amoxicillin-resistant Streptococcus pneumoniae can be resensitized by targeting the mevalonate pathway as indicated by sCRilecs-seq. Elife 11, e75607. 10.7554/eLife.75607. (IF=8.713)
  5. Minhas, V., Domenech, A., Synefiaridou, D., Straume, D., Brendel, M., Cebrero, G., Liu Xue, Costa, C., Baldry, M., Sirard, J.-C., et al. (2023). Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence. PLoS Biol 21, e3001990. 10.1371/journal.pbio.3001990. (IF=9.163)
  7. Dong, N., Zeng, Y., Wang, Y., Liu, C., Lu, J., Cai, C., Liu Xue, Chen Yongkui, Wu, Y., Fang, Y., et al. (2022). Distribution and spread of the mobilised RND efflux pump gene cluster tmexCD-toprJ in clinical Gram-negative bacteria: a molecular epidemiological study. Lancet Microbe 3, e846–e856. 10.1016/S2666-5247(22)00221-X. (IF=86.208)
  9. Huang, W., Zhang, J., He, Y., Hu, C., Cheng, S., Zeng, H., Zheng, M., Yu, H., Liu, Xue, Zou, Q., et al. (2022). A cyclic adenosine monophosphate response element-binding protein inhibitor enhances the antibacterial activity of polymyxin B by inhibiting the ATP hydrolyzation activity of CrrB. Front Pharmacol 13, 949869. 10.3389/fphar.2022.949869. (co-corresponding, IF=4.225)
  1. Clement Gallay, Stefano Sanselicio, Mary E. Anderson, Young Min Soh, Xue Liu, Gro A. Stamsås, Simone Pelliciari, Renske van Raaphorst, Julien Dénéréaz, Morten Kjos, Heath Murray, Stephan Gruber, Alan D. Grossman & Jan-Willem Veening. (2021) CcrZ is a pneumococcal spatiotemporal cell cycle regulator that interacts with FtsZ and controls DNA replication by modulating the activity of DnaA replication by modulating the activity of DnaA. Nat Microbiol 6, 1175–1187. https://doi.org/10.1038/s41564-021-00949-1 (IF=30.964)
  1. Zhu D*, Wang L*, Shang G*, Liu Xue*, Zhu J*, Lu D, Kan B, Zhang JR, Xiang Y. (2014). Structural Biochemistry of a Vibrio cholerae Dinucleotide Cyclase Reveals Cyclase Activity Regulation by Folates. Molecular Cell 55:931-937. (*Co-first author, IF=16.133)
  1. Liu, B.*, Liu Xue*, Zhang, J., & Liu, G. (2017). A Natural Lipotrisaccharide and Its Derivatives Selectively Lyse Streptococcus pneumoniae via Interaction with Cell Membrane. ACS Infectious Diseases. (*Co-first author, IF=4.97)
  1. Pan S*, Liu Xue*, Xie Y, Yi Y, Li C, Yan Y, Liu Y. (2010). Esterification Activity and Conformation Studies of Burkholderia cepacia Lipase in Conventional Organic Solvents, Ionic Liquids and Their Co-solvent Mixture Media. Bioresource Technology 101:9822-9824. (Co-first author, IF=7.27)
  1. Huang, X., Wang, J., Li, J., Liu, Y., Liu Xue, Li, Z., Kurniyati, K., Deng, Y., Wang, G., Ralph, J.D., et al. (2020). Prevalence of phase variable epigenetic invertons among host-associated bacteria. Nucleic Acids Res 48, 11468–11485. (IF=11.797)
  1. Yang, H., Liu Xue, Li, Q., Li, L., Zhang, J.R., and Tang, Y. (2016). Total Synthesis and Preliminary SAR study of (+/-)-merochlorins A and B. Organic & biomolecular chemistry 14, 198-205. (IF=3.135)
  1. He, L., Nair, M.K., Chen, Y., Liu Xue, Zhang, M., Hazlett, K.R., Deng, H., and Zhang, J.R. (2016). The Protease Locus of Francisella tularensis LVS Is Required for Stress Tolerance and Infection in the Mammalian Host. Infection and Immunity 84, 1387-1402. (IF=3.401)
  1. Wen, Z., Sertil, O., Cheng, Y., Zhang, S., Liu Xue, Wang, W.C., and Zhang, J.R. (2015). Sequence elements upstream of the core promoter are necessary for full transcription of the capsule gene operon in Streptococcus pneumoniae strain D39. Infection and Immunity 83, 1957-1972. (IF=3.401)
  1. Song YX, Li QL, Liu Xue, Chen YC, Zhang Y, Sun AJ, Zhang WM, Zhang JR, Ju JH. 2014. Cyclic Hexapeptides from the Deep South China Sea-Derived Streptomyces scopuliridis SCSIO ZJ46 Active Against Pathogenic Gram-Positive Bacteria. Journal of Natural Products 77:1937-1941. (IF=3.990)